Alpha-lipoic acid is an organic compound in the body that acts as a potent antioxidant. Alpha-lipoic acid may have several health benefits, like helping reduce oxidative stress and helping the body control blood sugar levels.

While the body naturally produces alpha-lipoic acid (ALA), people can boost their levels by making suitable dietary choices, taking supplements, or both.

Supplementing with ALA may aidTrusted Source the management of chronic conditions resulting from oxidative stress, including diabetic neuropathy.

In this article, learn about its effectiveness, possible benefits, and side effects.

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ALA is present within mitochondria, the powerhouses of the cells. It is crucial for digestion, absorption, and the creation of energy. It helps enzymes turn nutrients into energy. It also has antioxidant properties.

Research into the efficacy of ALA in disease management is mixed. There are no Food and Drug Administration-approved indicationsTrusted Source for ALA as a dietary supplement.

Neuropathy

The antioxidant properties of ALA supplementation may aidTrusted Source the management of neuropathies resulting from oxidative stress, such as diabetic neuropathy. Supplementation may reduce symptoms of burning, pain, or numbness.

However, supplementation should never replace traditional treatments

Weight loss

Some claim that ALA may help people with obesity lose small amounts of body weight.

However, studies also show that the impact of ALA on weight loss is small. According to a 2018 analysisTrusted Source, those taking ALA supplements only lost an average of 1.52 pounds and did not experience a significant change in their waist circumference.

Cholesterol levels

ALA supplementation may help decrease total and low-density lipoprotein cholesterol, according to a 2019 reviewTrusted Source. However, overall lifestyle and diet changes are typically the more effective means of managing cholesterol rather than focusing on specific supplements.

PCOS

Studies suggest that ALA can be an effective complementary therapy in the management of polycystic ovary syndrome. The authors of a 2023 review attributed this to the positive effect ALA had on fasting blood sugar levels and insulin resistance

Other conditions

Various studies have assessed the use of ALA in the treatment of:

However, research in these areas is limited. More studies are needed before ALA can be recommended to treat these conditions.

Doctors consider ALA to be safe for most people, with little to no risk of side effects. Mild effects may include nausea, rashes, and itching if a person takes high doses.

It is essential for people considering taking ALA supplements to talk with their doctor to see if it is right for them.

ALA is an organic compound that acts as an antioxidant and has a variety of other effects on the body. While the body makes it naturally, some people also take ALA supplements.

ALA is generally safe for adults, but it is best to speak with a doctor before taking any new supplements.